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Lorient, The Finest
The Finest Experience
Lorient is a premium cross-linked hyaluronic dermal filler that has established a foothold for entry into the worldwide beauty market by proving the safety and quality suitable for global standards through the acquisition of this European certification.
Product
Product name
Ingredient
Shelf life
Approval
Lorient Fine / Lorient Filler / Lorient Volume
20 mg/mL Cross-linked Hyaluronic Acid / 0.3% Lidocaine
36 Months from the manufacturing date
European EC Certified, MFDS Approved
Smooth and Natural
The Artistic Tool
If one could write letters with a filler, a practitioner could freely shape the desired shape on a face, as easy as writing letters. Unlike a poorly made pen with inconsistent bursts of ink, we wanted to present excellence and comfort with smoothness and elegance.
Smooth and Comfortable
Lorient presents a low and consistent injection force, which allows precise procedures at the intended area effortlessly with the exact intended amount. The possibility of tissue damage could be reduced as well, due to the low pressure of the gel when entering the facial tissue that is sensitive. Therefore, even patients who are new to a dermal filler procedure can experience it with no worries.
Smooth and Natural
Just being smooth is not a requirement for a good filler. A good filler should not only be smooth but also maintain its shape while staying in the right place without flowing down. After being injected smoothly into the skin, Lorient enables the desired volume and natural shapes to show with its specially designed properties.
Delicate and Firm
STORM™, The Technology Behind Lorient's Quality
Each chain of hyaluronic acid is weak. We weaved these chains delicately and densely into a 3-dimensional network with a large porous structure. The specialty in this technology lies in the creation of the solid porous structure from use of minimal crosslinking agents.
Structure Full of Life
This solid structure plays a significant role as a support in your skin for as long as it is needed and provides the mechanical strength to maintain volume. However, unlike structural architecture built from tons of concrete, Lorient's porous network structure acts as passages for cells, water molecules, oxygen, and nutrients. Therefore, this structure naturally sits within the tissue, full of life.
Long-Lasting Beauty
Our technology-integrated structure occupies a space within the skin while augmenting the volumizing capacity. Moreover, being similar to the structure of the dermis, it naturally settles naturally with excellent longevity.
Clean and Safe
Sometimes, Less Is More
BDDE, the crosslinking agent for hyaluronic acid, enables a dermal filler to have more longevity and viscoelastic properties. However, when it does not participate in crosslinking, the residual BDDE is classified as a hazardous substance. After years of research, we have developed a technology that enables us to remove residual BDDE efficiently. But... what if it was possible to reduce the amount of BDDE used at all? If longevity and viscoelasticity are controlled by the amount of crosslinking agent used, then more would be used to reach higher longevity and viscoelastic properties. However, we have found that this could increase residual BDDE, and also cause the gel to be excessively hard causing difficulty to the practitioner. To solve such issues, we have successfully developed a technology that increases the efficiency of crosslinking. Now, even with the use of minimal BDDE, we are still able to achieve our desired viscoelastic properties for a filler that would result to more natural and safer results.
Controlling Aspects Invisible to the Naked Eye
We seriously considered our role as a manufacturer when it comes to the side effects of fillers. We wanted to manufacture a filler - considered a medical device - with the same strict specifications as pharmaceuticals. By complying with pharmaceutical GMP standards, we control everything in the production process from incoming of materials to release of finished products very strictly with most procedures being performed in cleanroom areas. As a result, this enables us to prevent the inflow of insoluble particles and microbes invisible to the naked eye (as small as 25 microns), which can cause inflammatory reactions.
Beyond General Standards
We believe that maintaining high purity is the easiest way to ensure the reliability of our product. Such is the reason why we purposely set standards more stringent than general standards regarding impurities. As a result, we could reduce the amount of residual BDDE and endotoxin to levels not only less than our strict in-house standards, but also lower than the detection limits of high-grade testing equipment.
Where it Should Be
Familiar to Your Body
We conducted endless research to make Lorient similar to the human skin, for you to feel as if it was originally a part of your body. For your body not to recognize the filler as a foreign substance and minimize side effects caused by immune reactions, Lorient has components similar to the skin. Lorient was designed to have an osmotic pressure of 300 mOsm/kg, which is extremely close to the environment in human body. Therefore, when injected, the sense of being a foreign body and pain would be minimized.
Inevitable Results
With a filler that settles as if it is your own skin tissue, barely causes side effects. We proved that Lorient is safe and reliable through the comparative clinical study with a world-leading product globally recognized for its safety and efficacy for decades. With this safety proven by actual data, Lorient has obtained the approval from the Korean MFDS and the European EC certification.
Make Your Selfie Match Your Mirror Image
Many misunderstand that the purpose of a filler is only to fill wrinkles and lift up the facial skin. Lorient does not agree with such thoughts. Beyond simply filling for volume, a dermal filler should turn your desired look into a reality. Just as you have imagined, making your selfie feel closer to your real look. This is Lorient's definition, the essence of a filler. "as if it has always been a part of you "always been". Your wanted image has always been your reality-
Research
1. Smooth and Safe Injection
Lorient shows a low and consistent injection force of a mere 7~8N (measured with 27G needles). This allows for a smooth and effortless filler injection, which reduces tissue damage and improves the safety of procedures.
2. Strict and Thorough Purity Control
Lorient is manufactured in the production line designed for pharmaceutical injectables. Complying with GMP standards not only for medical devices but also for pharmaceuticals, we reduced impurities in our fillers significantly with the use of clean rooms and building-wide HVAC equipment.
3. With Comfort, Similar to Human Body
Lorient shows an osmotic pressure of 300 mOsm/kg, which is very similar to the osmotic pressure of human blood. This allows for the human body to feel Lorient to be less of foreign body after injection. Our in-house test data shows that Lorient's osmotic pressure is closer to blood in the body in comparison to other dermal fillers.
4. Until Impurity Is Not Detected
Residual crosslinking agent (BDDE) and endotoxin are rigorously controlled since they might cause inflammatory reactions. When residual amounts were measured, there was no detection, which confirms that both impurities exist less than the limit of detection.
Publications
Guide Book
Lee, W. Safe filler injection techniques : an illustrated guide. Springer.
Paper
Lee, W.; Rho, N-K.; Yang,E-J. Determination of Hyaluronic Acid Dermal Filler Impurities Using SEM/EDS Analysis.
Paper
Rho, N.-K.; Goo, B.L.; Youn,S.-J.;Won, C.-H.; Han, K.-H. Lip Lifting Efficacy of Hyaluronic Acid Filler Injections: A Quantitative Assessment Using 3-Dimensional Photography.
Paper
Lee, W. (2023). Hyaluronic Acid Filler Injection Guided by Doppler Ultrasound.
Paper
Lee W, Park J-W,Yang E-J. Temple augmentation by injecting a hyaluronic acid filler between the superficial and deep temporal fasciae.
Paper
Yi, K.-H., Oh, W., Kim, H. M., Ahn,H.-S., Hu, H., & Kim, H.-J. (2023). Anatomical proposal for hyaluronic acid filler injection in subzygomatic arch depression: A dual-plane injection technique.
Paper
Yi, K.-H., Lee, J.-J., Hur, H.-W., Bae,H., & Kim, H.-J. (2022). Hyaluronic acid filler injection for deep nasolabial folds: A novel intraoral approach.
Paper
Lee, W. (2022) Five Factors to Consider before Treatment of a Hyaluronic Acid Filler-Induced Vascular Complications
Paper
Lee, W., Koh, I. K., Kim, K. M., Kim, K. M., Kim, K. H., Kim, S., H. (2023). Assessing the Practical Application of Rheological Properties of Hyaluronic Acid Fillers- A 1 year Follow-Up Photographic Analysis
History
08 / 2020
European EC Certified
Lorient with lidocaine was approved for sales in Europe.
07 / 2020
European EC Certified
Lorient without lidocaine was approved for sales in Europe.
07 / 2020
MFDS Approved
Lorient with lidocaine was approved for sales by MFDS.
01 / 2020
Clinical Trial Completed
Lorient's competitiveness was proved through a comparative study with global-leading products.
06 / 2019
Clinical Trial Started
Lorient was also developed to compete with other global-leading products. One of the highest-appreciated dermal fillers was chosen as the comparative group of the clinical study.
12 / 2018
3rd Generation Process
Scale-Up Completed
Finally, global-leading quality has been achieved. We have obtained the optimal filler properties, using the minimal amount of crosslinking agent.
01 / 2018
2nd Generation Process
Scale-Up Completed
To achieve global-leading quality, we continued to complete the right process development.
06 / 2017
1st Generation Process
Scale-Up Completed
We could not be satisfied by "mediocre quality", so we started the process of developing a global-leading product.
01 / 2017
Formulation Completed
We discovered right properties for a dermal filler, obtained through crosslinking hyaluronic acid.
01 / 2018
Initiation of Dermal Filler Research
Yearning for beauty not to be disturbed with side effects, we started developing a quality dermal filler product.
